Parkinson’s Disease also known as Paralysis Agitans
Parkinsonism is a condition that causes a combination of the movement abnormalities such as rigidity, tremor, slow movement, impaired speech, muscle stiffness or partial or complete loss of muscle movement known as hypokinesia etc.
It is a disorder of the nervous system that worsens over time. The nervous system is a network of nerve cells that controls many parts of the body, including movement.
Most common signs & symptoms.
Symptoms often begin on one side of the body, then affect both sides.
- Tremors – usually the first symptom that generally begins in one upper extremity, where the head may be involved, and such tremors disappear during sleep
- Or tremor in just one hand or sometimes a foot or the jaw.
- Shaking in the hands, arms, legs, jaw, or head, especially when resting.
- Shake less when you’re doing some sort of task or moving around.
- Rigidity that is somehow present to equal extent in opposing muscle groups, If a limb is passively moved, the rigidity gives way with a series of slight jerks.
- Difficulty in initiating movements or slowness in executing movements
- An inability to make adjustments to the posture of the body
- Infrequent blinking
- Impaired ocular convergence
- Slow monotonous speech, without typical speech patterns.
- Reduced swinging of arms while walking
- The whole body moves in one mass when the patient turns
- Physical movements are slower than normal, which can make it hard to do everyday tasks
- Short tottering steps, often rising on the toes and leaning forward
- One may rub their thumb and forefinger back and forth – known as a pill-rolling tremor.
- Postural disturbances
- Difficulty in rising from chair
- Difficulty in rolling over in bed
- Slurred speech
- Stopped posture
- Gait or balance disturbances
- The trunk appears stiff or freeze
- A decrease in sexual desire or performance
- Deep cramping sensations
- Excessive daytime sleepiness or fatigue
- Anxiety, depression or apathy
- Dementia with a prominent lack of motivation, or with hallucinations
- A serious or angry look on the face, even when are not in a bad mood
- Postural hypotension
- Tendency to fall
- Lack of energy while walking
- Dyskinesia – a group of involuntary movements
- Swinging movements of limbs and trunk
- Essential tremors
- Tremor worse with posture and action
- Tremors with no rigidity
- Aches and cramps in the muscles and joints, especially in the neck and back
- Drooling saliva
- Skin or vision changes
- Weight changes
- Constipation
- Nonmotor symptoms – may include acting out dreams, needing to urinate often, trouble smelling – have difficulty identifying certain odors or the difference between odors, problems with thinking and memory, and feeling very tired.
POSSIBLE CAUSES & RISK FACTORS
- Idiopathic with unknow causes
- Specific genetic changes are linked to Parkinson’s disease.
- In Parkinson’s disease, nerve cells in the brain – dopamine and norepinephrine called neurons slowly break down or die.
- The presence of Lewy bodies. Clumps of specific substances within brain cells are microscopic markers of Parkinson’s disease.
- Post-encephalitic Parkinsonism
- Lack of blood supply to the cerebrum
- Cerebral arteriosclerosis – thickening of the walls of the arteries due to aging or hypertension
- As a sequelae of various infectious process e.g. viral encephalitis
- Exposure to certain toxins or other environmental factors may increase the risk such as herbicides, pesticides, carbon monoxide, manganese, carbon disulphide
- Drugs- reserpine, phenothiazines, alpha methyldopa, butyrophenones, haloperidol
- Wilson’s disease
- Degeneration of the cerebellum
- Syphilitic mesencephalitis
- Very rare tumors of the brain stem
- The risk of Parkinson’s disease increases with age. Usually, it starts around age 60 or older.
- Men are more likely to develop Parkinson’s disease than are women.
Self-care, DO’S AND DONT’S
- Always carry an identity card with important telephone numbers Or take someone along while going out.
- Use a stick for support while walking.
- Take care of the cause of anxiety or stress.
- Avoid handling delicate articles.
- Inform banks or other necessary places about your disease and the subsequent change in your signature.
- Exercise or walk regularly as walking is known to increase brain activity.
- Eat nutritious food.
- Avoid alcohol and smoking.
Although Parkinson’s disease can’t be fully cured, some remedies may help symptoms get better.
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