Peripheral neuropathy is a nerve related disorder when the nerves that are found outside of the brain and spinal cord (peripheries) are damaged.
The peripheral nervous system is responsible for sending signals from the brain and spinal cord to the rest of the body.
That can often cause weakness, numbness and pain (stabbing, burning or tingling), usually in the hands and feet.
The main types of peripheral neuropathy include:
- Sensory neuropathy – that carry messages of touch, temperature, pain and other sensations to the brain.
- Motor neuropathy – control movement
- Autonomic neuropathy – that control involuntary processes, such as digestion, bladder function and control of blood pressure
- Mononeuropathy – damage to a single nerve outside of the central nervous system
Misc. signs & symptoms for all 4 types may include:
- Every nerve in the peripheral system has a specific job. Symptoms depend on the type of nerves affected.
- Pins and needles in the affected parts
- Numbness or less ability to feel pain or changes in temperature, particularly in your feet
- A burning or sharp pain, usually in the feet
- Unusual tingling
- Feeling pain even from a very light touch (e.g., trigeminal neuralgia)
- Loss of balance or co-ordination
- Twitching and muscle cramps
- Muscle weakness or paralysis
- Thinning (wasting) of muscles
- Difficulty lifting up the front part of your foot and toes.
- Constipation or diarrhoea, particularly at night
- Feeling sick, bloating and belching
- Low blood pressure – or feeling faint or dizzy when you stand up
- Rapid heartbeat (tachycardia)
- Excessive sweating or a lack of sweating
- Feeling as if you’re wearing gloves or socks when you’re not.
- Heat intolerance.
- Sexual issues in men such as erectile dysfunction
- Difficulty emptying your bladder of urine
- Loss of bowel control
- Altered sensation or weakness in the fingers
- Double vision
- Problems with focusing your eyes
- Bell’s palsy – eye pain or weakness of one side of your face
- Foot or shin pain
- Carpal tunnel syndrome – tingling, pain or numbness in the fingers.
- Changes in skin, hair, or nails
- Emotional disturbances
Possible Causes & Risk Factors
- Diabetes neuropathy – uncontrolled high sugar levels in blood in diabetes can damage nerves.
- Autoimmune conditions (Sjogren’s syndrome, lupus, rheumatoid arthritis, Guillain-Barre syndrome) – when immune system can mistakenly attack the peripheral nerves, causing inflammation etc.
- traumatic injuries on nerves
- infections – viral or bacterial infections e.g., Lyme disease, shingles, hepatitis B and C, diphtheria, and HIV.
- metabolic disorders
- Genetic or inherited
- exposure to toxins or poisons
- Tumors or cancerous growths.
- Bone marrow disorders.
- Other metabolic conditions such as kidney or liver disease, and an underactive thyroid etc.
- Alcohol use disorder.
- Certain medicines, especially chemotherapy.
- Low B vitamins, including B1, B6 and B12, as well as copper and vitamin E are crucial to nerve health.
- Repetitive motion, such as those performed for certain jobs.
Further Complications
Complications of peripheral neuropathy can include:
Burns, infections, skin injuries and wounds especially on the feet, as the patients may not feel temperature changes or pain on parts of your body that are numb.
Weakness and loss of sensation may be associated with lack of balance and falling.
Prevention. Self-care
- Identify and manage the underlying causes that put you at risk.
- Make healthy lifestyle choices
- Check the affected body parts regularly, wear close-toed, well-fitting shoes and treat minor injuries before they become infected, especially if you have diabetes.
- Installing handrails in the bathroom
- Use canes or walkers and ensure that you are walking only in well-lit rooms that can decrease fall risk.
- Eat a diet rich in fruits, vegetables, whole grains and lean protein to keep nerves healthy.
- Protect against low levels of vitamin B12 by eating meats, fish, eggs, low-fat dairy foods and fortified cereals that are a good source of vitamin B12.
- Exercise regularly, try to get at least 30 minutes to one hour of exercise at least three times a week.
- Avoid factors that may cause nerve damage such as repetitive motions, exposure to toxic chemicals, smoking and drinking too much alcohol.
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